Research
Imaging · Circuits · Sensors
Research Field 01
Live-Cell Imaging
CH1
Two sister cells, same genes, same dish — and different choices. We film them long enough to see why.
- 01GrowCells in microfluidic traps
- 02ImageEvery 5 min for up to 7 days
- 03SegmentFind every cell in every frame
- 04TrackLink frames into family trees
- 05ModelFit timing and noise
Instruments
| Widefield | Inverted, 3 channels, stage incubator |
|---|---|
| Spinning disk | 63× oil, 4 lasers, fast z-stacks |
| Microfluidics | Custom PDMS traps, 8 parallel conditions |
| Compute | GPU workstation for segmentation |
Recent papers
- Intl. Journal
A memory circuit that records transient stress in single yeast cells
- Preprint
Self-supervised segmentation of dividing cells with fewer than 50 labels
- Domestic Conf.
형광 이미지 기반 단일세포 스트레스 반응 시점 분석
Projects
- Ongoing2024–2027
Single-cell timing of stress responses in yeast
Microfluidic time-lapse imaging of 10,000+ cells to map how fast individual cells switch on stress genes.
Funded by National Research Foundation (fictional)
- Completed2022–2025
Light-controlled gene expression for tissue patterning
Optogenetic promoters that let us draw stripes of gene expression onto a layer of cells with blue light.
Funded by University Seed Grant (fictional)
- Completed2021–2024
Open-source pipeline for cell tracking
A tracking and lineage tool that turns raw time-lapse stacks into family trees of dividing cells.
Funded by Open Science Fund (fictional)