Research
Imaging · Circuits · Sensors
Research
Research Overview
Three fields, one toolkit — and the resources we share.
One question, three ways in: why do identical cells behave differently?
We watch the difference happen, we rebuild the circuits that cause it, and we put those circuits to work as sensors. Each field feeds the others — imaging tells circuit design what to build, and sensors are circuits that have left the lab bench.
- 01Live-Cell ImagingWatching single cells decide, divide and respond in real time with time-lapse fluorescence microscopy.
- 02Synthetic Gene CircuitsDesigning genetic switches, timers and counters that make cells behave predictably.
- 03Biosensor EngineeringTurning engineered cells into reporters that light up when they detect metabolites or toxins.
Open Resources
Plasmids
pLUM-Sense + 14 constructs
Reporter, logic-gate and biosensor plasmids shared through a public repository.
LumenTrack
Python · MIT licence
Segmentation and lineage tracking for time-lapse movies.
Protocols
9 protocols
Microfluidic loading, paper-strip printing and ratiometric analysis.